found that under the induction of hypoxic stress in breast cancer cells, some tRFs derived from tRNAAsp, tRNAGlu, tRNAGly and tRNATyr can suppress the stability of multiple oncogenic transcripts by displacing their 3’ UTR from the RBP YBX1 and eventually inhibit the proliferation of breast cancer cells (35). This evidence concerns the gene YBX1 and breast cancer.