In particular, increased NCAPG2 levels were found to have a significant correlated various infiltrating inflammatory cells, including macrophages, M2 macrophages, regulatory NK cells, cancer-associated fibroblasts (CAFs), T cells (Tregs), CD8+ T cells, CD4+ T cells, B cells, monocytes, neutrophils, and others, in BRCA, CESC, ESCA, DLBC, HNSC, GBMLGG, GBM, KIRC, KIRP, KIPAN, KICH, LIHC, LUAD, LGG, LUSC, OV, MESO, STAD, SARC, STES, SKCM, PRAD, PAAD, THYM, TGCT, and THCA (P < 0.05). The gene discussed is CD4; the disease is cancer.