It compels the downregulation of the β-tubulin proteins in cancer cells and impairs the activity of CDK1 and cyclin B1 to inhibit the progression of the cell cycle.348 Its active epimer, 7-epi-cluisianone, succeeded in bringing about cell death in 25 cancer cell lines out of 60 human cancer cell types through the modification of the immune system, prevention of angiogenesis, along with cancer cell invasion in the body. The gene discussed is CDK1; the disease is cancer.