From the gene expression data, we observed pathways associated with immune response, antigen presentation, cytokine cascades, etc.; pathways associated with tumor initiation and growth signals such as NOTCH1 and MYC but also pathways associated with tumor suppression such as TP53 and PTEN signaling; and finally, pathways associated with apoptosis, hypoxia, and reactive oxygen species. This evidence concerns the gene NOTCH1 and neoplasm.