CD274 and neoplasm: To evaluate the potential function of exosomal PD‐L1 in the tumor microenvironment, the low‐expressing exosomal PD‐L1 LNCaP cell line was co‐cultured with activated T‐cells and supplemented with exosomes derived from PC3 cells with PD‐L1 knocked out (Exo‐PD‐L1KO) or overexpressed (Exo‐PD‐L1HA).