The expression of FasL (CD178) on the surface of NK-92 cells co-cultured with HCC SK-Hep1 cells was increased by the blocking of IL-6 compared to non-blocking (Fig. S3A, Non-treated 10.31%, Anti-IL-6 14.87%, *p < 0.05), in addition, it was significantly restored to HIF-1α-expressed HCC cells (CoCl2 6.84%, CoCl2 + Anti-IL-6 8.65%). This evidence concerns the gene HIF1A and hepatocellular carcinoma.