Moreover, although miR-27b has been reported to regulate cancer cell invasion and migration in EC [17], the present study showed that RBAT1 and miR-27b had no obvious role in regulating the invasion (Supplemental Fig. 2A) and migration (Supplemental Fig. 2B) of Ishikawa and HEC-1B cells. This evidence concerns the gene E2F3-IT1 and cancer.