TNFRSF17 and acute myeloid leukemia: In this regard, a work by Nair-Gupta et al. showed that co-culture of bone marrow stromal cells with AML or MM cells prevented the lysis of tumor cells in vitro and in vivo by anti-CD3 × anti-CD123 or anti-CD3 × anti-BCMA Duobodies, respectively [18].