RIPK1 and colorectal carcinoma: Furthermore, IHC of RIP1 and β-catenin using a CO952a TMA consisting of primary CRC tissues (n = 10) and metastatic tissues (n = 10), such as lymph nodes (LN), ovaries, and lungs, indicated that the expression levels of RIP1 and β-catenin were elevated in metastatic tissues (Fig. 1E).