Carlo Pescia contributed LYWS-1212 involving the sudden onset of oral and lingual aphthous ulceration in a 38-year-old male composed of CD3+ CD4+ PD1+ and frequent CD30+ lymphocytes and eosinophils with a monoclonal TR gene rearrangement that spontaneously regressed; the panel considered this as a form of CD30+ lymphoproliferative disorder most consistent with traumatic ulcerative granuloma with stromal eosinophilia [90] (Fig. 10M and N). This evidence concerns the gene TNFRSF8 and lymphoproliferative syndrome.