SP100 and infection: We identified texture features of seven markers, DEAD (Asp-Glu-Ala-Asp) box helicase 6 (DDX6), phospho-cyclin dependent kinase 9 (p-CDK9), RNAP II phospho-Ser2, RNAP II phospho-Ser5, NRF2, speckled protein 100 kDa (SP100), and total protein staining, that alone detected infection with good prediction accuracy, indicating that infection changed the subcellular distribution of these markers.