We identified texture features of seven markers, DEAD (Asp-Glu-Ala-Asp) box helicase 6 (DDX6), phospho-cyclin dependent kinase 9 (p-CDK9), RNAP II phospho-Ser2, RNAP II phospho-Ser5, NRF2, speckled protein 100 kDa (SP100), and total protein staining, that alone detected infection with good prediction accuracy, indicating that infection changed the subcellular distribution of these markers. The gene discussed is CDK9; the disease is infection.