RORA and Parkinson disease: Hence, protein expression levels of RORA in the SNpc in female controls were three-fold greater than in male controls (P < 0.01 and Fig. 1A, C) (female control: 1.358 ± 1.118, male control: 0.328 ± 0.077) and in PD this was elevated 2-fold in males relative to controls (P < 0.01), but unchanged in females (male PD: 0.922 ± 0.291, female PD: 1.641 ± 1.697) Fig. 1B.