To this end we implanted AT3-OVA tumor cells into the inguinal mammary fat pads of floxed control versus Lck-Cre;Ptp1bfl/fl or Lck-Cre;Ptpn2fl/fl T cell-specific PTP1B- or PTPN2-deficient female mice respectively and monitored tumor growth (Fig. 5a). This evidence concerns the gene PTPN2 and neoplasm.