The repression of tumor growth and the recruitment of T cells, including cytotoxic CD8+ T cells, was generally more pronounced when PTPN2 was deleted in T cells (Fig. 5a, b), whereas the repression of tumor growth by Compound 182 more closely resembled the effects of deleting PTP1B in T cells (Fig. 5a, b). Here, CD8A is linked to neoplasm.