INS and type 2 diabetes mellitus: Here, we combine a mechanistic model with a data-driven model to identify factors predictive of inter-individual differences in glucose and insulin dynamics following an oral glucose tolerance test (OGTT) in a large group (n = 2968) of individuals with various glucometabolic status (including normal glucose metabolism (NGM), prediabetes, as well as T2DM) participating in a population-based cohort study (The Maastricht Study) [19].