Their increase in the periphery in T1D participants herein may reflect thymic output, increased expansion, and/or differentiation to stem cell memory T cells (CD45RA+CXCR3+CCR7+CD27+CD28+CD95+) (75), which could not be distinguished from naive T cells in this data set. The gene discussed is CXCR3; the disease is type 1 diabetes mellitus.