A recent bioinformatics analysis shows that fibrillar collagens I (COL1A1, COL1A2) and III (COL3A1), as well as COL6A1, COL6A2, COL6A3, COL4A1, COL4A2, COL18A1 , and COL12A1 are upregulated in BC (40). This evidence concerns the gene COL12A1 and breast cancer.