Transgenic aP2-ALOX15 mice were tested in comparison with Alox15 knockout mice (Alox15−/−) and corresponding wildtype control animals (C57BL/6J) in the complete Freund’s adjuvant induced hind-paw edema model and in the dextran sulfate sodium induced colitis (DSS-colitis) model. Here, ALOX15 is linked to colitis.