In terms of impact on heart conditions and development of dilated cardiomyopathy, impairment of the lamin A/C gene is a well-known factor (50) and results in conduction problems, arrhythmias, atrioventricular block and sudden cardiac death (51–55) with at least 260 LMNA mutations having been linked to cardiac diseases (56). The gene discussed is LMNA; the disease is atrioventricular block.