CTLA4 and colitis: Patients that were colitis-free following anti-CTLA-4 immunotherapy had a higher abundance of bacteria belonging to the families Bacteroidaceae, Rikenellaceae and Barnesiellaceae, with a model trained on these reads able to categorize patients with a sensitivity of 70% and specificity of 100%.122 Another study analyzing fecal samples of patients following anti-CTLA-4 immunotherapy found that responders were enriched in Faecalibacterium spp.