And observe Immunohistochemistry images of CDKN2A (Figure 6 (A)-(D)), SERPINE1 (Figure 6 (F)-(I)), MMP3 (Figure 6 (K)-(N)), IOD values in five genes were differentially expressed in normal and cancer tissues (Figure 6 (E), 6 (J), 6 (O)). The gene discussed is MMP3; the disease is cancer.