A prime example of the importance of parsing the different types of dementia exposure (compared with limiting to family history only) that we identified in the current review was the differential patterns of results obtained between individuals who had a positive APOE status (i.e., genetic susceptibility to AD) and those who were caregivers or spouses of those with dementia (i.e., nonfamilial exposure) on SCD reporting. Here, APOE is linked to Alzheimer disease.