NLRP1 and lung adenocarcinoma: Additionally, a biological analysis of lung adenocarcinoma (LUAD) data from the TCGA and GEO databases found that the levels of NLRP1 mRNA were significantly lower in LUAD tissues than in non-cancerous lung tissues, and that LUAD progression was negatively associated with NLRP1 expression, in terms of clinical features such as tumor pathological stage, lymph node metastasis, and primary tumor status.