TRIM21 and peeling skin syndrome: Patients in the pSS group were found to have elevated serum IgG levels (17.98 ± 7.72 versus 12.94 ± 3.09 g/L, p < 0.01), ANA-positive status (94.3% versus 65%, p < 0.01), anti-Ro52-positive status (77.1% versus 45%, p < 0.01), and anti-SSB-positive status (41.4% versus 0, p < 0.001).