We found that XPO1 expression was upregulated in HCC tissues, which was consistent with previous reports (Figure 5g).7 Besides, HCC patients with elevated XPO1 expression showed inferior survival, and moreover, the combination of both DBF4 and XPO1 high expression yielded the worst prognosis (Figure 5h-i). This evidence concerns the gene DBF4 and hepatocellular carcinoma.