NFE2L2 and squamous cell carcinoma: ALKBH5-mediated m6A demethylation at two m6A residues in the 3'UTR of NFE2L2/NRF2 mRNAs, which are recognized by IGF2BP2, contributes to reduced mRNA stability and decreased NFE2L2/NRF2 expression in hypopharyngeal squamous cell carcinoma cells171.