FTH1 and lung adenocarcinoma: For example, in patients with lung adenocarcinoma (LUAD), the m6A reader insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) is highly expressed and binds to m6A-marked mRNAs encoding anti-ferroptosis regulators (e.g., SLC3A2, GPX4, ACSL3, and ferritin heavy chain 1 (FTH1)) to increase the stability of these mRNAs164.