MACC1 and melanoma: Furthermore, analyses of the correlation between MACC1 and MET expression suggest that coexpression of intermediate to high levels of MACC1 and MET may be associated with metastasis of cutaneous melanoma, whereas the nonparallel expression of MACC1 and MET in benign nevi and primary melanomas suggests that the interplay between MACC1 and MET signaling might not be involved in the benign melanocytic lesions or early stages of melanomas.