Various types of T lymphocytes, such as activated T helper (Th) 1, Th17, and autoreactive CD4+ T cells, and the secretion of pro-inflammatory cytokines such as interleukin (IL)-17, IL-23, IL-6, and TNF-α, are mainly responsible for the development of RA [3–6]. This evidence concerns the gene IL17A and rheumatoid arthritis.