Other inflammation-associated genes such as triggering receptors expressed on myeloid cells (TREM)1 and TREM2, mediating infection-related inflammation [29], genes linked to antiviral response (APOBEC3A, OASL) and genes not involved in counter-infection mechanisms but associated with cell cycle regulation (HMGA2, CCNB1, FOSL1) and lipid metabolism (LIPG, PCSK9, APOL1, FABP5) were also upregulated (Fig. 5A). The gene discussed is TREM2; the disease is infection.