Furthermore, the IHC staining results for patient-19, patient-5, and patient-21, presented in Fig. 1, highlight three conditions, namely positive HFG staining in NAT and tumor tissue (Fig. 1a, b), negative HFG staining in NAT and positive HFG staining in tumor tissue (Fig. 1c, d), and negative HFG staining in both tumor tissue and NAT (Fig. 1e, f). This evidence concerns the gene BRD2 and neoplasm.