2011; Al-Amin et al. 2016), which found that LPS is implicated in the depletion of endogenous antioxidant enzymes like CAT and SOD. A related study revealed that prenatally LPS-exposed rats resulted in a significant reduction in the levels of SOD and CAT in the midbrain of female offspring (Sharma et al. 2017). Furthermore, short- and long-term effects of LPS were found to induce endotoxemia in mouse ovarian tissue (Shokrizadeh et al. 2019). Moreover, LPS injected into pregnant mice affects the behavior of their offspring in adulthood (Chlodzinska et al. 2011). Here, SOD1 is linked to serum lipopolysaccharide activity.