PRKAA2 and breast cancer: In the last, in order to evaluate the diagnostic power of the AMPK-GSDMD axis in breast cancer, we obtained three breast cancer proteomic datasets from previous proteomic studies and performed survival analyses using the Kaplan-Meier plotter to determine the correlation between overall survival (OS) and the level of GSDMD, AMPKα, or pT172-AMPKα [37, 38].