The PPI networks of each mutated EGFR protein were then established with 62/178, 76/210, 39/83, and 92/217 node/edges based on the connectivity and the number of PPIs presented in topology for PC9, CL68, H3255, and H1975 NSCLC cells, respectively (supplemental Fig. S2). Here, EGFR is linked to non-small cell lung carcinoma.