To investigate the effect of BART2-5p on DICER1, we transfected BART2-5p mimics into EBV-negative NPC cell lines 5-8F, 6-10B, HONE1, HNE1, and a normal nasopharyngeal epithelial cell line NP69, or transfected BART2-5p inhibitor into EBV-positive NPC cells HONE1-EBV, and analyzed the expression changes of DICER1. This evidence concerns the gene DICER1 and nasopharyngeal carcinoma.