The circular RNA hsa_circRNA_102908 is originated from the BRCA1 associated RING domain 1 and has been already found significantly up-regulated in human radioresistant esophageal cancer cell line KYSE-150R when compared with the parental cell line KYSE-150, suggesting its possible involvement in the development of radiation resistance and treatment failure [62]. The gene discussed is BARD1; the disease is esophageal cancer.