CD8A and chronic obstructive pulmonary disease: To study fibrocyte- CD8+ T cells interplay in vitro, blood samples were obtained from a separate cohort of COPD patients, (i.e. COBRA (Bronchial Obstruction and Asthma Cohort; sponsored by the French National Institute of Health and Medical Research, INSERM, Ethics committee number: 2008-A00294-51/1), as outpatients in the Clinical Investigation Centre of the University Hospital of Bordeaux.