Next Generation Sequencing (NGS) panels did not reveal pathogenic mutations, but genetic variants of CFH and MCP genes associated with a higher risk of the disease (homozygous polymorphism p.V62I for CFH – associated with C3G – and homozygous polymorphism C.*897 T > C for MCP – associated with the atypical haemolytic uremic syndrome (aHUS)). This evidence concerns the gene CFH and atypical hemolytic-uremic syndrome.