Moreover, Soleimani et al. [41] reported that activated NF-κB cascade potentiated colon cancer proliferation, survival, angiogenesis, and metastasis leading to its progression via upregulation of the anti-apoptotic Bcl-2 expression, hence inhibiting the cellular apoptosis [42]. The gene discussed is NFKB1; the disease is malignant colon neoplasm.