The HNE1-LMP1 cells were subcutaneously injected into nude mice to grow NPC-LMP1 xenograft tumors, and then the plasmid of LMP1-shRNA1, LMP1-shRNA2, and sh-control were injected through the caudal vein at indicated time points, as shown in Figure 4A. The gene discussed is PDLIM7; the disease is nasopharyngeal carcinoma.