Many researches have proved that DUBs involve in the regulation of some cancer‐related pathways, such as Akt (protein kinase B), Wnt/β‐catenin signaling, transforming growth factor‐β, and NF‐κB (nuclear factor kappa‐light‐chain‐enhancer of activated B cells).52, 53, 54, 55. Here, NFKB1 is linked to cancer.