The AGS, MKN-45G, and KATO III human gastric adenocarcinoma cell lines were selected on the basis of strong positive gastrin expression, whereas a gastrin-expressing subclone of the GLUTag murine enteroendocrine tumor cell line was used as model of NETs because is secretes hormones including gastrin (33). The gene discussed is GAST; the disease is gastric adenocarcinoma.