Norrie's disease and familial exudative vitreoretinopathy (FEVR) are retinal conditions, which present similarly to ROP engendered, engendered by a single genetic variant many of which overlap with ROP including NDP, FZD4 TSPAN12, and LRP5 from our analysis. The gene discussed is FZD4; the disease is Familial exudative vitreoretinopathy.