We retrieved 4881 RA-related pathogenic genes from the GeneCards database (https://www.genecards.org/ ), and analyzed the expression levels of the top 20 genes and found that the expression of HLA-B, MIF, PSTPIP, TLR1 differed in the two groups (Figure 6A). This evidence concerns the gene PSTPIP1 and rheumatoid arthritis.