MYH14 and B-cell chronic lymphocytic leukemia: Actin and myosin work as actomyosin complex to regulate cell contraction and cellular tension.42–46 We further analyzed the colocalization of actin and myosin in both primary HD-B and CLL cells (HD-B donors n = 2; CLL patients n = 6) to further study how the spatial arrangement of myosin motors at the cortex affects cortical tension and the possible involvement of this complex in CLL pathogenesis.