NLRP1 and myocardial infarction: Local injection of DNase-conjugated gold particles (AuNPs) into the rat myocardium can produce a 50% TNF-α knockout efficiency producing a significant anti-inflammatory effect, improving the acute cardiac function after myocardial infarction; therefore, TNF-α may be a potential treatment for myocardial infarction.24 On the basis of all the evidence, we believe that NLRP1 may affect the occurrence and prognosis of MVA in patients with STEMI by regulating the inflammatory response and many inflammatory factors.