Table-III indicated that the NLRP1 expression was associated with smoking history, LVEF, Gensini score, MAV incidence and mortality (P<0.05), but not with age, gender, BMI, history of hypertension, diabetes or hyperlipidemia. To assess the diagnostic performance of NLRP1, the ROC curve analysis selected 292.2 pg/ml as the best cutoff value for NLRP1 (AUC=0.886; 95% CI: 0.835–0.937; sensitivity, 100.0%; specificity, 67.2%, P<0.001). Thus, the NLRP1 level should be useful to predict the occurrence of MVA in patients with STEMI. (Fig.3) This evidence concerns the gene NLRP1 and hyperlipidemia.