On the other hand, the majority of the compounds significantly regulated the molecular mechanisms of cancer in mammalian systems, including P53 Signaling, Apoptosis Signaling, and Aryl Hydrocarbon Receptor Signaling (Fig.1B), and utilized the TP53 signaling pathway to effectively induce cell death and apoptosis in tumor cell lines (Fig.1C). The gene discussed is AHR; the disease is cancer.