The dysregulation of cytokine production in the striatum and cortex of patients suffering from HD includes IL-6 (interleukin-6), IL-1, IL-8, MMP-9, and TNF α (Kalonia et al., 2011a; Kalonia et al., 2011b; Mehta et al., 2013; Chen et al., 2014). Here, IL6 is linked to Huntington disease.