ALK: anaplastic lymphoma kinase; BID: twice daily; EGFR: epidermal growth factor receptor; KRAS: Kirsten rat sarcoma viral oncogene homolog; NSCLC: non-small cell lung cancer; OD: once daily; RET: rearranged during transfection; ROS1: c-ROS oncogene. The gene discussed is BID; the disease is non-small cell lung carcinoma.