Lin et al studied 61 patients with CRSwNP and found that phospho-janus kinase 2 (p-JAK2), IL-5, IL-6, and granulocyte-colony stimulating factor (G-CSF) were correlated with LMK-CT and SNOT-22 scores.57 Patients were categorized into “mild” and “severe” CRS based on Lund–Kennedy score alone, and data on patients with CRSsNP was limited. This evidence concerns the gene IL6 and chronic rhinosinusitis with nasal polyps.