Confirming the recalcitrance of high MYC non‐NE SCLC tumors (Alves Rde et al, 2014), of 50 hallmark gene sets, we found that the 2 gene sets predictive of MYC activity, MYC‐targets‐V1 and MYC‐targets‐V2, were, respectively, the first and third most highly associated with platinum resistance in SCLC patients (Horita et al, 2015; Liberzon et al, 2015; Appendix Fig S2E). The gene discussed is MYC; the disease is small cell lung carcinoma.