For example, we identified the driver gene set including ATR, COL4A2, and FLT1 in GBM individual TCGA‐12‐0821, and the Dscores of dysfunctional cancer hallmarks showed significant correlation with Escores of these cancer hallmarks (PCC = 0.86 and P = 1.25e‐08). Here, COL4A2 is linked to cancer.